Overview
The UniFuge Mini is a user-friendly, automated batch centrifuge for low-shear separation of mammalian, bacterial, and insect cell lines. This scaled-down version of the UniFuge Pilot is perfect for cleanrooms, laminar flow hoods, and benchtops. It features a single-use module (rotor and separation chamber) and integral tube set that comes gamma irradiated to ensure easy installation, clean-up, and disposal, making it ideal for de-risking scale-down studies before transitioning to larger-scale bioprocesses.
BENEFITS:
- Low noise level (below 80dB) during operation
- Continuous discharge of supernatant and intermittent discharge of cell culture
- Reduces host cell proteins and other contaminants
- Compatible with various processing volumes and concentration targets
- Designed for fluid transfer with temperatures in the range of 4-38 °C (39-100 °F)
- Available in two minimum working volume options: Micro (90mL) or Mini (300mL)
Technical Details
Rec. Processing Volume | Micro - 0.5 - 10L Mini - 5L - 25L |
Max Flow Rate | 50 - 1000mL/min |
Rotational Force | 300 to 4,000 x g |
Weight | 45 kg (100lbs) |
Maxiumum Case Pressure | 4.5 - 6.6 bar (65 - 95 psi) |
Progamable Logic Controllers (PLC) | Allen-Bradley® |
Feed | Center for low-shear operation |
Power Configurations | Single-phase universal power supply 100 to 240 volts, 50/60 Hz, suitable for global use |
Pneumatic | Clean, dry air supply 4.5 - 6.6 bar (65 - 95 psi), 57 standard Liters per Minute (SLPM), 2 Standard Cubic Feet per Minute (SCFM) |
How It Works
Balancing centrifugal forces and fluid flow rates, the UniFuge cell processing platform gently concentrates cells in the tubular bowl while the supernatant (cell-free media or buffer) flows into a collection chamber. The concentrated cells can then be washed or exchanged with another medium or buffer within the same closed chamber. Once the module fills with cells, the controller stops the rotor to automatically collect the cell concentrate. This cycle repeats until cell processing is complete.
The UniFuge Mini Features
- Fully automated, intuitive software accessible through a PLC colour touchscreen and HMI Touchscreen 22.9 cm (9”) - 16:9 aspect ratio
- Four pinch valve configuration: Feed, Concentrate, Supernatant and Buffer
- CE Compliant Design
- Benchtop footprint
- Optional Supervisory Control and Data Acquisition (SCADA) via Ethernet connection
- cGMP compliance with standards, including Federal Regulations (21 CFR Part 11) data trail
More on Carr Biosystems
Carr Biosystems is a global leader in the design and manufacture of liquid/solid centrifugal separation systems. Their range of continuous flow centrifuges offers the ability for true scale up of contained processes, from development to production for microbial, yeast, animal cell and fine chemical applications. All centrifuge systems are developed in a state of the art manufacturing facility in Clearwater, Florida. BPES have worked with Carr Centritech in the UK since 1997.
