Adjustable Mixing Technology
A defining feature of Leadgene’s C.BIRD, C.NEST 2.0 and S.NEST 2.0 systems is their patented pneumatic mixing technology. When enabled, this mixing improves nutrient distribution and oxygen transfer, supporting more uniform cell growth and higher reproducibility.
This technology allows researchers to conduct high-throughput, parallel experiments under conditions that better reflect larger-scale bioprocesses, bridging the gap between early-stage screening and process development. By integrating defined pneumatic mixing, the systems enable more accurate assessment of media, feeds and cell line performance, ultimately improving data quality and experimental confidence.
C.BIRD
- Compact, fits inside standard incubators
- Patented mixing improves nutrient and oxygen distribution
- Supports reproducible small-scale experiments in 24- and 96-well formats
- User-friendly software for streamlined operation
C.NEST 2.0
- Optional pneumatic mixing for improved nutrient and oxygen distribution
- Can also perform static culture for sensitive experiments
- Integrated incubation maintains consistent temperature, CO₂, and humidity
- Ideal for parallel screening and early-stage process optimisation
- Optional UV sterilisation for maintaining aseptic chamber conditions
S.NEST 2.0
- Optional pneumatic mixing enhances culture uniformity and performance
- Supports static culture workflows when required
- Real-time pH and dissolved oxygen (DO) monitoring for enhanced insight
- Dedicated incubator environment enables consistent multi-well experimentation
- Optional UV sterilisation for maintaining aseptic chamber conditions
Technical Specifications
S.NEST 2.0 | C.NEST 2.0 | C.BIRD | |
Mixing rate (sec/cycle) | 10–50 (±5%) | 10–50 (±5%) | 15–50 (±2%) |
Suspension boost | Yes | Yes | N/A |
Throughput | 96 × 4 / 24 × 4 | 96 × 4 / 24 × 4 | 96 × 3 / 24 × 3 |
Medium Volume (µL/well) | 1000–1600 150–200 | 1000–1600 150–200 | 1000–1600 150–200 |
Incubation chambers | 4 | 4 | N/A |
Temperature Control (°C) | (RT+10) to 40 | (RT+10) to 40 | N/A |
CO₂ Control (%) | 1–20 | 1–20 | N/A |
Humidity Monitoring | Yes | Yes | N/A |
UV light Sterilization | Yes | Yes | N/A |
Data Output | DO / pH | N/A | N/A |
Automation Compatibility | Yes | Yes | N/A |
Workstation | Yes | Yes | N/A |
More on Leadgene Biosolutions
Leadgene Biosolutions (formerly Cytena BPS), founded in 2018, is a specialist provider of advanced micro‑scale bioprocess technologies, including the C.BIRD, C.NEST 2.0 and S.NEST 2.0 systems, designed to support early‑stage development, cell culture optimisation and data‑driven bioprocess decision making. In 2025, the company transitioned into an independent identity through integration with Leadgene Biomedical, uniting academic innovation, international experience and real‑world insight within a unified biosolutions organisation
