Description
S-I Series: SIP and CIP Customisable Industrial Scale Bioreactors/Fermenters
The S and I series consist of highly automated pilot-industrial fermenters and bioreactors, available from 5 up to 30,000 litres and more (S series 5 – 200 L; I series 300 – 30,000 L). These fermentation units are completely customisable, tailor-made starting from the clients’ specific requests.
- Customisable culture vessels from 5 L to 30,000 L
- Instrumentation for control and measurement of pH, dO2, CO2, RPM, gas mixing, temperature, anti-foam, feeds, total cell density and viable cell density measurement, weight, redox, conductivity, Level, etc.
- SCADA Control System SBC-16
- Software management data – trends
- Designed for microbial and cell fermentation, for batch, fed-batch and continuous processes
- Complete range of accessories
- Brushless motor for agitation system
Fermenters / Bioreactors
SIP and CIP Customisable Pilot and Industrial Scale Fermenters/ Bioreactors
The Solaris S-I can be used for; Pilot scale process development, Scale up and scale-down studies and production.
Features
- Top quality stainless steel with excellent finishing and high technology.
- Insulated vessels, with the possibility of passivation.
- Different H/D ratios.
- Different types of finishing (mirror polish, scotch brite, electropolishing, etc.).
- Different types of agitation (top-bottom, single or double mechanical seal with lubrication loop, magnetic stirrer).
- Different types of thermoregulation loops (from basic to completely closed).
- Microbial (aerobic, anaerobic) and cell cultures configurations available.
- Suitable for batch, fed-batch and continuous processes.
- Several gas mixing strategies with a selectable number of rotameters, TMFCs or solenoid valves, for air, O 2, CO 2 and N 2.
Benefits
- Wide range of measurement and control options including temperature, pH, dO 2, dCO 2, redox, antifoam, level, conductivity, weight, cell density (total cells, viable cells), etc.
- Modbus digital sensors.
- Stainless-steel industrial PCS LEM_2, with a selectable number and type of peristaltic pumps.
- cGMP certifiable.
- Easy to access service lines, to easily perform maintenance.
- The systems can be integrated with tanks (feeding tanks, mixing tanks, harvest tanks, etc.), CIP/SIP systems, centrifuges, filtration systems, and many more ancillary equipment.
Leonardo: Supervisory Control Software
Leonardo is the Process Control System (PCS) software installed across the full Solaris product range, including benchtop bioreactors and fermenters, pilot and industrial systems, and tangential flow filtration (TFF) platforms. Using a common software environment across all scales helps simplify training, day-to-day operation, and process scale-up.
The software is web-based and supplied on a 24” all-in-one touchscreen interface running a Linux operating system. Leonardo communicates with one or more Siemens PLCs to control, monitor, and record all relevant process parameters throughout cultivation or filtration runs.
Real-time process data is displayed clearly to the user, providing immediate visibility of key operating conditions and system performance. Historical data logging, trend analysis, and process records are also available to support development work, optimisation, and batch traceability.
Leonardo is designed to be intuitive and easy to navigate. Pages are clearly structured around their relevant functions, allowing users to access controls, trends, recipes, calibration tools, and alarms efficiently. An integrated context-help manual is included within the software, explaining the purpose of each on-screen function and helping new users become confident quickly.
The result is a powerful yet user-friendly control platform that supports both routine operation and advanced process development, while maintaining a consistent user experience from benchtop scale through to production systems.
Industrial Automation Options
Solaris industrial bioreactors and fermenters are available with two automation architectures, allowing customers to select the level of control integration best suited to their facility standards, control philosophy, and site infrastructure.
PCS Solution 1 - Solaris Managed Control System
In this configuration, Solaris supplies a complete Process Control System (PCS) with Siemens PLC hardware, with all sequences, logic, and process control functions managed directly through the Solaris automation platform.
This is the preferred option for customers seeking a fully integrated turnkey solution, where vessel operation, recipes, alarms, trending, and process automation are controlled through the Solaris Leonardo software environment.
For plant-wide integration, customer systems can connect to the Solaris PCS via Ethernet, PROFINET, or PROFIBUS, enabling data transfer to a site DCS, SCADA platform, or historian for control room monitoring and process data analysis. Solaris also supports wider third-party integration options including API, Siemens S7 communication, and OPC UA where required.
PCS Solution 2 - Customer Managed Control Architecture
In this configuration, Solaris supplies the full mechanical system together with automation hardware and a distributed I/O architecture, while all sequences and control logic are managed by the customer or appointed system integrator.
This approach is typically selected by organisations with established site-wide automation standards or existing DCS/SCADA infrastructure, where centralised control from the customer’s own platform is preferred.
Solaris provides the required instrumentation, field devices, and distributed I/O framework, allowing straightforward integration into the customer’s preferred control environment.
Flexible Integration for Industrial Facilities
Both options are designed to support GMP manufacturing environments, scalable process automation, and integration with wider plant systems. This allows customers to choose between a fully managed Solaris controls package or alignment with existing in-house automation standards."
More on Solaris
Solaris Biotech benchtop fermenters and bioreactors offer efficient platforms for R&D and product development applications. Their broad range of products are flexible and easy to use, ensuring there is always a solution specific to your needs and requirements – from research scale of a few hundred ml up to cGMP production of > 2000L.
Benefits include compact and user friendly designs, parallel software platform, up-to-date and open communication protocols.
The product range is used in universities, schools and research centres, as well as in pharma, nutraceutical, cosmeceutical, chemical, agricultural, and food and beverage industries, not to mention bioplastics and biofuels applications.
Solaris Tangential Flow Filtration (TFF) systems, fully automated within the Kronos product line, combine industrial elements and a compact design. For larger scale TFF applications open to customisation, consider the Tytan platform.
