MTI Bioscience’s thermal sterilisers and can be used for applications ranging from media sterilisation through to viral inactivation. Flow rates range from 0.3L/min up to 12L/min. The systems are fully automated and can be customised to your exact requirements.
 
MTI Bioscience is a division of Microthermics who have been active in the food and beverage sector since 1989 where continuous processing and sterilisation is common place.

Continuous Thermal Process Flow-Diagram and Time-Temperature History

What is Continuous Thermal Sterilisation

In Continuous Thermal Sterilisation (CTS), media is pumped through:

• Heat exchangers to rapidly heat it to process temperatures of 138-150°C
• An insulated hold tube to retain it at temperature for just a few seconds
• Cooling heat exchangers to rapidly cool it to the required finish temperature
• The resulting overall heat exposure of the media is a fraction of what it sees in traditional autoclave processes.
• Additionally, the heat exposure is completely uniform.

Benefits

• Produces High Quality/Highly functional media with no degradation due to variable or prolonged heat exposure typical of autoclave and large volume bioreactors.
• Gentle process, can produce media failing in autoclave sterilisation and scale-up.
• Produces Completely Uniform Media o No variation within batch or from batch to batch like from autoclaving
• More energy, time and manpower efficient than autoclaving.
• Scalable – scaling to larger or smaller batches is quick and easy
• Real-time process validation to cGMP requirements due process control and stability
• Highly flexible configuration can easily switch from one product to another. Ideal for R&D and rapid production environments.